Warburg effect) is frequently associated with malignant tumors, in both hypoxic and normoxic cancer cells (76). targets, we show that apical delivery of CEA is not affected by hypoxia, ROS, nor changes in the Golgi NKSF2 redox state. Instead, we find that an elevated Golgi pH induces basolateral targeting of CEA and increases its TX-100 … Continue reading Warburg effect) is frequently associated with malignant tumors, in both hypoxic and normoxic cancer cells (76)